For people with personal web pages, like mine, the addition of this additional information tagging won’t net any real benefits, as near as I can tell. Not to mention that, at this point in time, the addition of “itemscope” and “itemtype”, as shown in this example:
<div itemscope itemtype="http://schema.org/Movie">
<h1>Avatar</h1>
<span>Director: James Cameron (born August 16, 1954)</span>
<span>Science fiction</span>
<a href="../movies/avatar-theatrical-trailer.html">Trailer</a>
</div>
would tend to throw warnings in all of the currently used markup validators (e.g. http://validator.w3.org/, etc.), making it seem that the page is no longer “standards compliant”, which is technically true. For myself, that part alone will prevent me from “taking advantage” of this, since I’m very particular about my pages being able to honestly display valid markup logos.
For most commercial websites, however, this can help to make their site more “target oriented”, sharpening the focus on the correct demographic range they wish to reach, thus improving the site’s chances of success in reaching the intended audience. This is going to affect SEO for nearly every site out there, at some point, so many companies (the vast majority, I’d imagine) would almost “have to” make use of this micro-format as soon as possible, or risk seeing their positions in the major search engines suffer.
At least, this is how I see it.